The research of the NMR group aims at gaining fundamental insight into molecular processes using solution and solid-state NMR spectroscopy as the main biophysical experimental techniques. Novel research concepts are being developed and applied to complex biomolecular systems including protein-protein and protein-nucleic acid complexes or membrane proteins. Additional research is conducted on heterogeneous systems such as hydrogels and liposomes. The facility is part of the Bijvoet Center for Biomolecular Research.

SPECIFICATIONS MAIN EQUIPMENT:

As a national and European large scale facility, state-of-the-art instrumentation for NMR experiments on soluble molecules or heterogeneous preparations (solid-state NMR) is available. Currently, NMR fields range from 500 MHz to 900 MHz (solution NMR) and from 500 MHz to 700 MHz (solid-state NMR). In addition, high sensitivity (DNP) solid-state NMR at 400 and 800 MHz will be installed starting in the middle of 2011. The NMR facility also functions as an European computational e-Infrastructure for NMR and structural biology. The computational infrastructure consists of several linux clusters with over 500 CPU cores. It also provides access to GRID computing. Further information can be obtained from the web site.

AVAILABILITY:
The Utrecht Facility is a national and european research infrastructure for solution and solid-state NMR, as well as computational structural biology with access for local, national and international researchers. Further information can be obtained from www.nmr.chem.uu.nl

CONTACT:

Dr. Hans Wienk : h.l.j.wienk@uu.nl

Solid-state NMR: Prof.dr. Marc Baldus, , m.baldus@uu.nl

Solution-state NMR: Prof. dr. Rolf Boelens, r.boelens@uu.nl

WEBSITE:
NMR